GCSF for Febrile Neutropenia during Cancer Therapy

Use of Hematopoietic Growth Factors in the Survival and Differentiation of Hematopoietic Cells.

Use of Hematopoietic Growth Factors in the Survival and Differentiation of Hematopoietic Cells.

Charles L. Bennett, M.D., Ph.D., Benjamin Djulbegovic, M.D., Ph.D., LeAnn B. Norris, Pharm.D., and James O. Armitage, M.D.

N Engl J Med 2013; 368:1131-1139March 21, 2013DOI: 10.1056/NEJMct1210890

A woman receives a diagnosis of diffuse large B-cell lymphoma; a standard chemotherapy regimen is recommended. Use of prophylactic granulocyte CSF is considered. G-CSF stimulates proliferation of neutrophil progenitors and release of mature neutrophils from bone marrow.

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