Charles L. Bennett, M.D., Ph.D., Benjamin Djulbegovic, M.D., Ph.D., LeAnn B. Norris, Pharm.D., and James O. Armitage, M.D.
N Engl J Med 2013; 368:1131-1139March 21, 2013DOI: 10.1056/NEJMct1210890
A woman receives a diagnosis of diffuse large B-cell lymphoma; a standard chemotherapy regimen is recommended. Use of prophylactic granulocyte CSF is considered. G-CSF stimulates proliferation of neutrophil progenitors and release of mature neutrophils from bone marrow.